Q9JI45

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession Q9JI45_RAT; Q9JI45;
Entrez ID 3474
GenBank Protein ID
GenBank Nucleotide ID
Protein Name Mitochondrial transcription factor A (Fragment)
Gene Name Tfam; Mttfa
Organism Rattus norvegicus
NCBI Taxa ID 10116
Sequence
(Fasta)		MALFRGMWGV LRTLGRTGVE MCAGCGGRIP SPV 34

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1MethylationLung cancer/carcinomaP24367550
[Reference]: These results suggest that the expression of mtTFA mRNA and protein is down-regulated in the lung tissue from the COPD patients with squamous cell lung cancer, and the level of mtTFA protein is related to apoptosis of pulmonary vascular endothelial cells. Aberrant mtTFA methylation may also play an important role in the pathogenesis of COPD


※ PTM Sites

PTM Modification Sites