Q99795

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession GPA33_HUMAN; Q99795;
Entrez ID 10223
GenBank Protein ID
GenBank Nucleotide ID
Protein Name Cell surface A33 antigen (Glycoprotein A33)
Gene Name GPA33
Organism Homo sapiens
NCBI Taxa ID 9606
Functional DescriptionMay play a role in cell-cell recognition and signaling.
Sequence
(Fasta)		MVGKMWPVLW TLCAVRVTVD AISVETPQDV LRASQGKSVT LPCTYHTSTS SREGLIQWDK 60
LLLTHTERVV IWPFSNKNYI HGELYKNRVS ISNNAEQSDA SITIDQLTMA DNGTYECSVS 120
LMSDLEGNTK SRVRLLVLVP PSKPECGIEG ETIIGNNIQL TCQSKEGSPT PQYSWKRYNI 180
LNQEQPLAQP ASGQPVSLKN ISTDTSGYYI CTSSNEEGTQ FCNITVAVRS PSMNVALYVG 240
IAVGVVAALI IIGIIIYCCC CRGKDDNTED KEDARPNREA YEEPPEQLRE LSREREEEDD 300
YRQEEQRSTG RESPDHLDQ

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1GlycosylationAstrocytoma/Astrocytoma glioblastomaPN11215296462
[Reference]: Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines.
2GlycosylationAstrocytoma/Astrocytoma glioblastomaPN20015296462
[Reference]: Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines.
3GlycosylationAstrocytoma/Astrocytoma glioblastomaPN22315296462
[Reference]: Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines.

※ Disease Cross-ref Annotation

DatabaseAnnotation
GWASdb
(count: 12)
(view all)		rs10918613; Lung function (forced expiratory volume in 1 second to forced vital capacity ratio); lung disease
rs12133648; Response to mTOR inhibitor (rapamycin); renal cell carcinoma|breast cancer|non-small cell lung carcinoma|endometrial carcinoma|glioblastoma multiforme|mantle cell lymphoma
rs10918616; Response to mTOR inhibitor (rapamycin); renal cell carcinoma|breast cancer|non-small cell lung carcinoma|endometrial carcinoma|glioblastoma multiforme|mantle cell lymphoma
rs10918618; Response to mTOR inhibitor (rapamycin); renal cell carcinoma|breast cancer|non-small cell lung carcinoma|endometrial carcinoma|glioblastoma multiforme|mantle cell lymphoma
rs73028893; QRS duration in Tripanosoma cruzi seropositivity; Chagas disease|cardiomyopathy
rs10918619; Response to mTOR inhibitor (rapamycin); renal cell carcinoma|breast cancer|non-small cell lung carcinoma|endometrial carcinoma|glioblastoma multiforme|mantle cell lymphoma

※ PTM Sites

PTM Modification Sites
Phosphorylation
(count: 4)		 197       PASGQPVSLKNISTD     dbPAF
281       ARPNREAYEEPPEQL     dbPAF
301       EREEEDDYRQEEQRS     dbPAF
313       QRSTGRESPDHLDQ*     dbPAF