Q96KF2

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession PRAC1_HUMAN; Q96KF2;
Entrez ID 84366
GenBank Protein ID
GenBank Nucleotide ID
Protein Name Small nuclear protein PRAC1 (Prostate cancer susceptibility candidate protein 1) (Prostate, rectum and colon expressed gene protein)
Gene Name PRAC1; C17orf92; PRAC
Organism Homo sapiens
NCBI Taxa ID 9606
Sequence
(Fasta)		MLCAHFSDQG PAHLTTSKSA FLSNKKTSTL KHLLGETRSD GSACNSGISG GRGRKIP 58

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1MethylationProstate cancer/carcinoma/adenocarcinomaD24100630
[Reference]: IHC analysis revealed a significantly decreased immunoreactivity of PRAC protein in PCa tissues compared to benign prostatic hyperplasia (BPH) (p<0.0001). Thus, our findings suggest that the pathogenesis of PCa may be due to the expression levels of PRAC protein, and this protein can serve as a potential biomarker for the management of PCa


※ PTM Sites

PTM Modification Sites
Phosphorylation
(count: 4)		 39        HLLGETRSDGSACNS     dbPAF
42        GETRSDGSACNSGIS     dbPAF
46        SDGSACNSGISGGRG     dbPAF
49        SACNSGISGGRGRKI     dbPAF