| Tag | Content |
|---|---|
| UniProt Accession | SREC2_HUMAN; Q96GP6; |
| Entrez ID | 91179 |
| GenBank Protein ID | NM_153334.6; NM_182895.4; |
| GenBank Nucleotide ID | NP_699165.3; NP_878315.2; |
| Protein Name | Scavenger receptor class F member 2 (SRECRP-1) (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) |
| Gene Name | SCARF2; SREC2; SREPCR |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity). |
| Sequence (Fasta) | MEGAGPRGAG PARRRGAGGP PSPLLPSLLL LLLLWMLPDT VAPQELNPRG RNVCRAPGSQ 60 VPTCCAGWRQ QGDECGIAVC EGNSTCSENE VCVRPGECRC RHGYFGANCD TKCPRQFWGP 120 DCKELCSCHP HGQCEDVTGQ CTCHARRWGA RCEHACQCQH GTCHPRSGAC RCEPGWWGAQ 180 CASACYCSAT SRCDPQTGAC LCHAGWWGRS CNNQCACNSS PCEQQSGRCQ CRERTFGARC 240 DRYCQCFRGR CHPVDGTCAC EPGYRGKYCR EPCPAGFYGL GCRRRCGQCK GQQPCTVAEG 300 RCLTCEPGWN GTKCDQPCAT GFYGEGCSHR CPPCRDGHAC NHVTGKCTRC NAGWIGDRCE 360 TKCSNGTYGE DCAFVCADCG SGHCDFQSGR CLCSPGVHGP HCNVTCPPGL HGADCAQACS 420 CHEDTCDPVT GACHLETNQR KGVMGAGALL VLLVCLLLSL LGCCCACRGK DPTRRPRPRR 480 ELSLGRKKAP HRLCGRFSRI SMKLPRIPLR RQKLPKVVVA HHDLDNTLNC SFLEPPSGLE 540 QPSPSWSSRA SFSSFDTTDE GPVYCVPHEE APAESRDPEV PTVPAEAPAP SPVPLTTPAS 600 AEEAIPLPAS SDSERSASSV EGPGGALYAR VARREARPAR ARGEIGGLSL SPSPERRKPP 660 PPDPATKPKV SWIHGKHSAA AAGRAPSPPP PGSEAAPSPS KRKRTPSDKS AHTVEHGSPR 720 TRDPTPRPPG LPEEATALAA PSPPRARARA APRPLGAHGR RRSPAKRAEA ASMLAADVRG 780 KTRSLGRAEV ALGAQGPREK PAPPQKAKRS VPPASPARAP PATETPGPEK AATDLPAPET 840 PRKKTPIQKP PRKKSREAAG ELGRAGAPTL 871 |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 1) | MESH:C535909 ; Marden Walker like syndrome |
| GWASdb (count: 1) | rs1005640; Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption); hypertension |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 31) (view all) | 104 ECRCRHGYFGANCDT dbPAF
111 YFGANCDTKCPRQFW dbPAF 127 PDCKELCSCHPHGQC dbPAF 138 HGQCEDVTGQCTCHA dbPAF 142 EDVTGQCTCHARRWG dbPAF 367 ETKCSNGTYGEDCAF dbPAF |
| Ubiquitination (count: 1) | 503 RFSRISMKLPRIPLR PLMD |