Q80SY9

PTMD Annotation Information

※ Protein Information

Tag	Content
UniProt Accession	Q80SY9_MOUSE; Q80SY9;
Entrez ID	257632
GenBank Protein ID
GenBank Nucleotide ID
Protein Name	NOD2 (Nucleotide-binding oligomerization domain-containing protein 2)
Gene Name	Nod2; Card15
Organism	Mus musculus
NCBI Taxa ID	10090
Sequence (Fasta)	MCSQEEFQAQ RSQLVALLIS GSLEGFESIL DWLLSWDVLS REDYEGLSLP GQPLSHSARR 60 LLDTVWNKGV WGCQKLLEAV QEAQANSHTF ELYGSWDTHS LHPTRDLQSH RPAIVRRLYN 120 HVEAMLELAR EGGFLSQYEC EEIRLPIFTS SQRARRLLDL AAVKANGLAA FLLQHVRELP 180 APLPLPYEAA ECQKFISKLR TMVLTQSRFL STYDGSENLC LEDIYTENIL ELQTEVGTAG 240 ALQKSPAILG LEDLFDTHGH LNRDADTILV VGEAGSGKST LLQRLHLLWA TGRSFQEFLF 300 IFPFSCRQLQ CVAKPLSLRT LLFEHCCWPD VAQDDVFQFL LDHPDRVLLT FDGLDEFKFR 360 FTDRERHCSP IDPTSVQTLL FNLLQGNLLK NACKVLTSRP DAVSALLRKF VRTELQLKGF 420 SEEGIQLYLR KHHREPGVAD RLIQLIQATS ALHGLCHLPV FSWMVSRCHR ELLLQNRGFP 480 TTSTDMYLLI LQHFLLHASP PDSSPLGLGP GLLQSRLSTL LHLGHLALRG LAMSCYVFSA 540 QQLQAAQVDS DDISLGFLVR AQSSVPGSKA PLEFLHITFQ CFFAAFYLAV SADTSVASLK 600 HLFSCGRLGS SLLGRLLPNL CIQGSRVKKG SEAALLQKAE PHNLQITAAF LAGLLSQQHR 660 DLLAACQVSE RVLLQRQARA RSCLAHSLRE HFHSIPPAVP GETKSMHAMP GFIWLIRSLY 720 EMQEEQLAQE AVRRLDIGHL KLTFCRVGPA ECAALAFVLQ HLQRPVALQL DYNSVGDVGV 780 EQLRPCLGVC TALYLRDNNI SDRGARTLVE CALRCEQLQK LALFNNKLTD ACACSMAKLL 840 AHKQNFLSLR VGNNHITAAG AEVLAQGLKS NTSLKFLGFW GNSVGDKGTQ ALAEVVADHQ 900 NLKWLSLVGN NIGSMGAEAL ALMLEKNKSL EELCLEENHI CDEGVYSLAE GLKRNSTLKF 960 LKLSNNGITY RGAEALLQAL SRNSAILEVW LRGNTFSLEE IQTLSSRDAR LLL 1014 Fasta Sequence >Q80SY9\|Nod2; Card15\|Mus musculus (Mouse) MCSQEEFQAQRSQLVALLISGSLEGFESILDWLLSWDVLSREDYEGLSLPGQPLSHSARRLLDTVWNKGVWGCQKLLEAVQEAQANSHTFELYGSWDTHSLHPTRDLQSHRPAIVRRLYNHVEAMLELAREGGFLSQYECEEIRLPIFTSSQRARRLLDLAAVKANGLAAFLLQHVRELPAPLPLPYEAAECQKFISKLRTMVLTQSRFLSTYDGSENLCLEDIYTENILELQTEVGTAGALQKSPAILGLEDLFDTHGHLNRDADTILVVGEAGSGKSTLLQRLHLLWATGRSFQEFLFIFPFSCRQLQCVAKPLSLRTLLFEHCCWPDVAQDDVFQFLLDHPDRVLLTFDGLDEFKFRFTDRERHCSPIDPTSVQTLLFNLLQGNLLKNACKVLTSRPDAVSALLRKFVRTELQLKGFSEEGIQLYLRKHHREPGVADRLIQLIQATSALHGLCHLPVFSWMVSRCHRELLLQNRGFPTTSTDMYLLILQHFLLHASPPDSSPLGLGPGLLQSRLSTLLHLGHLALRGLAMSCYVFSAQQLQAAQVDSDDISLGFLVRAQSSVPGSKAPLEFLHITFQCFFAAFYLAVSADTSVASLKHLFSCGRLGSSLLGRLLPNLCIQGSRVKKGSEAALLQKAEPHNLQITAAFLAGLLSQQHRDLLAACQVSERVLLQRQARARSCLAHSLREHFHSIPPAVPGETKSMHAMPGFIWLIRSLYEMQEEQLAQEAVRRLDIGHLKLTFCRVGPAECAALAFVLQHLQRPVALQLDYNSVGDVGVEQLRPCLGVCTALYLRDNNISDRGARTLVECALRCEQLQKLALFNNKLTDACACSMAKLLAHKQNFLSLRVGNNHITAAGAEVLAQGLKSNTSLKFLGFWGNSVGDKGTQALAEVVADHQNLKWLSLVGNNIGSMGAEALALMLEKNKSLEELCLEENHICDEGVYSLAEGLKRNSTLKFLKLSNNGITYRGAEALLQALSRNSAILEVWLRGNTFSLEEIQTLSSRDARLLL

※ PTM-Disease Association

Num	PTM	Disease	Cell Type	Type	PTM Site	PMID
1	Ubiquitination	Crohn's disease		P		23892723
1	[Reference]: Our findings identify RIP2 as a substrate for Pellino3 and Pellino3 as an important mediator in the Nod2 pathway and regulator of intestinal inflammation

※ Disease Cross-ref Annotation

Database	Annotation
CTD (Curated) (count: 8) (view all)	MESH:D015535 ; Arthritis, Psoriatic MESH:C538157 ; Blau syndrome MESH:D003093 ; Colitis, Ulcerative MESH:D003424 ; Crohn Disease MESH:D003872 ; Dermatitis MESH:D015212 ; Inflammatory Bowel Diseases MESH:C563714 ; Sarcoidosis, Early-Onset OMIM:617321 ; YAO SYNDROME

※ PTM Sites

PTM	Modification Sites