| Tag | Content |
|---|---|
| UniProt Accession | PAXI_RAT; Q66H76; |
| Entrez ID | 360820 |
| GenBank Protein ID | |
| GenBank Nucleotide ID | |
| Protein Name | Paxillin |
| Gene Name | Pxn |
| Organism | Rattus norvegicus |
| NCBI Taxa ID | 10116 |
| Functional Description | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). |
| Sequence (Fasta) | MDDLDALLAD LESTTSHISK RPVFLSEEPP YSYPTGNHTY QEIAVPPPVP PPPSSEALNG 60 TVLDPLDQWQ PSGSRYAHQQ PPSPSPIYSS STKNSSASNP QDSVGSLCSR AGEEEHVYSF 120 PNKQKSAEPS PTVMSSSLGS NLSELDRLLL ELNAVQRSPS GFSAGMVSVQ ASREPLGSWG 180 TEGRAIILSP FFQDEAESSP PLPGALSPLY GVPESNNLLG GKAGPLMKEK PKRNGGRGLE 240 DVRPSVESLL DELENSVPSP VPAITVNQGE MSSPQRVTSS QQQTRISASS ATRELDELMA 300 SLSDFKFMAQ GKTGSSSPPG GLSKPGSQLD SMLGSLQSDL NKLGVATVAK GVCGACKKPI 360 AGQVVTAMGK TWHPEHFVCT HCQEEIGSRN FFERDGQPYC EKDYHSLFSP RCYYCNGPIL 420 DKVVTALDRT WHPEHFFCAQ CGAFFGPEGF HEKDGKAYCR KDYFDMFAPK CGGCARAILE 480 NYISALNTLW HPECFVCREC FTPFVNGSFF EHDGQPYCEV HYHERRGSLC SGCQKPITGR 540 CITAMAKKFH PEHFVCAFCL KQLNKGTFKE QNDKPYCQSC FLKLFC 587 |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 4) | MESH:D002471
; Cell Transformation, Neoplastic MESH:D008546 ; Melanoma, Experimental MESH:D009362 ; Neoplasm Metastasis MESH:D002289 ; Carcinoma, Non-Small-Cell Lung |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 32) (view all) | 106 NPQDSVGSLCSRAGE dbPAF
109 DSVGSLCSRAGEEEH dbPAF 118 AGEEEHVYSFPNKQK dbPAF 119 GEEEHVYSFPNKQKS dbPAF 126 SFPNKQKSAEPSPTV dbPAF 130 KQKSAEPSPTVMSSS dbPAF |