Q15543

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession TAF13_HUMAN; Q15543;
Entrez ID 6884
GenBank Protein ID
GenBank Nucleotide ID
Protein Name Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18)
Gene Name TAF13; TAF2K; TAFII18
Organism Homo sapiens
NCBI Taxa ID 9606
Functional DescriptionComponent of the DNA-binding general RNA polymerase II transcription factor IID complex (TFIID). TFIID plays a critical role in the regulation of gene transcription in eukaryotic cells.
Sequence
(Fasta)		MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL 60
VIEFITEMTH KAMSIGRQGR VQVEDIVFLI RKDPRKFARV KDLLTMNEEL KRARKAFDEA 120
NYGS 125

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1Serine PhosphorylationMelanomaUS3317001009
[Reference]: Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy.

※ Disease Cross-ref Annotation

DatabaseAnnotation
CTD (Curated)
(count: 1)		OMIM:617432 ; MENTAL RETARDATION, AUTOSOMAL RECESSIVE 60
GWASdb
(count: 1)		rs28634276; Response to taxane treatment (placlitaxel); lung cancer

※ PTM Sites

PTM Modification Sites
Phosphorylation
(count: 1)		 33        GKRKRLFSKELRCMM     dbPAF
Ubiquitination
(count: 3)		 111       LTMNEELKRARKAFD     PLMD
115       EELKRARKAFDEANY     PLMD
34        KRKRLFSKELRCMMY     PLMD