Tag | Content |
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UniProt Accession | TF65_MOUSE; Q04207; |
Entrez ID | 19697 |
GenBank Protein ID | |
GenBank Nucleotide ID | |
Protein Name | Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) |
Gene Name | Rela; Nfkb3 |
Organism | Mus musculus |
NCBI Taxa ID | 10090 |
Functional Description | NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dim(view all) |
Sequence (Fasta) | MDDLFPLIFP SEPAQASGPY VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT 60 IKINGYTGPG TVRISLVTKD PPHRPHPHEL VGKDCRDGYY EADLCPDRSI HSFQNLGIQC 120 VKKRDLEQAI SQRIQTNNNP FHVPIEEQRG DYDLNAVRLC FQVTVRDPAG RPLLLTPVLS 180 HPIFDNRAPN TAELKICRVN RNSGSCLGGD EIFLLCDKVQ KEDIEVYFTG PGWEARGSFS 240 QADVHRQVAI VFRTPPYADP SLQAPVRVSM QLRRPSDREL SEPMEFQYLP DTDDRHRIEE 300 KRKRTYETFK SIMKKSPFNG PTEPRPPTRR IAVPTRNSTS VPKPAPQPYT FPASLSTINF 360 DEFSPMLLPS GQISNQALAL APSSAPVLAQ TMVPSSAMVP LAQPPAPAPV LTPGPPQSLS 420 APVPKSTQAG EGTLSEALLH LQFDADEDLG ALLGNSTDPG VFTDLASVDN SEFQQLLNQG 480 VSMSHSTAEP MLMEYPEAIT RLVTGSQRPP DPAPTPLGTS GLPNGLSGDE DFSSIADMDF 540 SALLSQISS |
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Database | Annotation |
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CTD (Curated) (count: 26) (view all) | MESH:D019969
; Amphetamine-Related Disorders MESH:D001471 ; Barrett Esophagus MESH:D002545 ; Brain Ischemia MESH:D001932 ; Brain Neoplasms MESH:D001943 ; Breast Neoplasms MESH:D002292 ; Carcinoma, Renal Cell |
PTM | Modification Sites |
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Phosphorylation (count: 14) (view all) | 131 RDLEQAISQRIQTNN dbPAF
176 AGRPLLLTPVLSHPI dbPAF 238 PGWEARGSFSQADVH dbPAF 276 SMQLRRPSDRELSEP dbPAF 306 EEKRKRTYETFKSIM dbPAF 311 RTYETFKSIMKKSPF dbPAF |
Acetylation (count: 1) | 310 KRTYETFKSIMKKSP PLMD |
Ubiquitination (count: 1) | 123 LGIQCVKKRDLEQAI PLMD |
Malonylation (count: 1) | 122 NLGIQCVKKRDLEQA PLMD |
Network | Interaction | ||
---|---|---|---|
A | B | Source | |