P35716

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession SOX11_HUMAN; P35716;
Entrez ID 6664
GenBank Protein ID
GenBank Nucleotide ID
Protein Name Transcription factor SOX-11
Gene Name SOX11
Organism Homo sapiens
NCBI Taxa ID 9606
Functional DescriptionTranscriptional factor involved in the embryonic neurogenesis. May also have a role in tissue modeling during development.
Sequence
(Fasta)		MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK RPMNAFMVWS 60
KIERRKIMEQ SPDMHNAEIS KRLGKRWKML KDSEKIPFIR EAERLRLKHM ADYPDYKYRP 120
RKKPKMDPSA KPSASQSPEK SAAGGGGGSA GGGAGGAKTS KGSSKKCGKL KAPAAAGAKA 180
GAGKAAQSGD YGGAGDDYVL GSLRVSGSGG GGAGKTVKCV FLDEDDDDDD DDDELQLQIK 240
QEPDEEDEEP PHQQLLQPPG QQPSQLLRRY NVAKVPASPT LSSSAESPEG ASLYDEVRAG 300
ATSGAGGGSR LYYSFKNITK QHPPPLAQPA LSPASSRSVS TSSSSSSGSS SGSSGEDADD 360
LMFDLSLNFS QSAHSASEQQ LGGGAAAGNL SLSLVDKDLD SFSEGSLGSH FEFPDYCTPE 420
LSEMIAGDWL EANFSDLVFT Y 442

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1MethylationNasopharyngeal carcinomaP24188789
[Reference]: SOX11 gene methylation may be plays a role in growth and invasion of nasopharyngeal carcinoma cells.

※ Disease Cross-ref Annotation

DatabaseAnnotation
CTD (Curated)
(count: 4)		MESH:D003528 ; Carcinoma, Adenoid Cystic
OMIM:615866 ; MENTAL RETARDATION, AUTOSOMAL DOMINANT 27
MESH:D009361 ; Neoplasm Invasiveness
MESH:D012468 ; Salivary Gland Neoplasms

※ PTM Sites

PTM Modification Sites
Phosphorylation
(count: 13)
(view all)		 113       RLKHMADYPDYKYRP     dbPAF
116       HMADYPDYKYRPRKK     dbPAF
129       KKPKMDPSAKPSASQ     dbPAF
133       MDPSAKPSASQSPEK     dbPAF
135       PSAKPSASQSPEKSA     dbPAF
137       AKPSASQSPEKSAAG     dbPAF
Glycation
(count: 2)		 140       SASQSPEKSAAGGGG     PLMD
158       GGGAGGAKTSKGSSK     PLMD

※ Protein-Protein Interaction

NetworkInteraction
ABSource