P30408

PTMD Annotation Information

※ Protein Information

Tag	Content
UniProt Accession	T4S1_HUMAN; P30408;
Entrez ID	4071
GenBank Protein ID
GenBank Nucleotide ID
Protein Name	Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1) (Tumor-associated antigen L6)
Gene Name	TM4SF1; M3S1; TAAL6
Organism	Homo sapiens
NCBI Taxa ID	9606
Sequence (Fasta)	MCYGKCARCI GHSLVGLALL CIAANILLYF PNGETKYASE NHLSRFVWFF SGIVGGGLLM 60 LLPAFVFIGL EQDDCCGCCG HENCGKRCAM LSSVLAALIG IAGSGYCVIV AALGLAEGPL 120 CLDSLGQWNY TFASTEGQYL LDTSTWSECT EPKHIVEWNV SLFSILLALG GIEFILCLIQ 180 VINGVLGGIC GFCCSHQQQY DC 203 Fasta Sequence >P30408\|TM4SF1; M3S1; TAAL6\|Homo sapiens (Human) MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLMLLPAFVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPLCLDSLGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQVINGVLGGICGFCCSHQQQYDC

※ PTM-Disease Association

Num	PTM	Disease	Cell Type	Type	PTM Site	PMID
1	Ubiquitination	Breast cancer/tumor/carcinoma	MCF-7 cell line	P		18270265
1	[Reference]: We found that L6-Ag is ubiquitylated and that ubiquitylation is essential for its function in cell migration

※ Disease Cross-ref Annotation

Database	Annotation
GWASdb (count: 2)	rs6440605; Smoking cessation; nicotine dependence rs6808255; Smoking cessation; nicotine dependence

※ PTM Sites

PTM	Modification Sites

※ Protein-Protein Interaction

Network

Interaction

A

B

Source

P11142	P30408	HPRD; IntAct; MINT
P15144	P30408	HPRD
P30408	P31689	HPRD; IntAct; MINT
P30408	P68366	HPRD; IntAct
P30408	Q08345	IntAct; MINT;HPRD
P30408	Q9H190	HPRD