| Tag | Content |
|---|---|
| UniProt Accession | CRYAB_RAT; P23928; |
| Entrez ID | 25420 |
| GenBank Protein ID | |
| GenBank Nucleotide ID | |
| Protein Name | Alpha-crystallin B chain (Alpha(B)-crystallin) |
| Gene Name | Cryab |
| Organism | Rattus norvegicus |
| NCBI Taxa ID | 10116 |
| Functional Description | May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. |
| Sequence (Fasta) | MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFST ATSLSPFYLR PPSFLRAPSW 60 IDTGLSEMRM EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR 120 KYRIPADVDP LTITSSLSSD GVLTVNGPRK QASGPERTIP ITREEKPAVT AAPKK 176 |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 14) (view all) | MESH:C563848
; Alpha-B Crystallinopathy MESH:D002292 ; Carcinoma, Renal Cell MESH:D002294 ; Carcinoma, Squamous Cell OMIM:615184 ; CARDIOMYOPATHY, DILATED, 1II MESH:D002386 ; Cataract OMIM:613763 ; CATARACT 16, MULTIPLE TYPES |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 3) | 19 RPFFPFHSPSRLFDQ dbPAF
45 FSTATSLSPFYLRPP dbPAF 59 PSFLRAPSWIDTGLS dbPAF |
| Acetylation (count: 6) | 103 DVIEVHGKHEERQDE PLMD
166 IPITREEKPAVTAAP PLMD 174 PAVTAAPKK****** PLMD 82 FSVNLDVKHFSPEEL PLMD 90 HFSPEELKVKVLGDV PLMD 92 SPEELKVKVLGDVIE PLMD |
| Ubiquitination (count: 9) (view all) | 103 DVIEVHGKHEERQDE PLMD
121 ISREFHRKYRIPADV PLMD 166 IPITREEKPAVTAAP PLMD 174 PAVTAAPKK****** PLMD 175 AVTAAPKK******* PLMD 72 LSEMRMEKDRFSVNL PLMD |