| Tag | Content |
|---|---|
| UniProt Accession | PTPRG_HUMAN; P23470; |
| Entrez ID | 5793 |
| GenBank Protein ID | NM_002841.3; XM_005265353.3; |
| GenBank Nucleotide ID | NP_002832.3; XP_005265410.1; |
| Protein Name | Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) |
| Gene Name | PTPRG; PTPG |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | Possesses tyrosine phosphatase activity. |
| Sequence (Fasta) | MRRLLEPCWW ILFLKITSSV LHYVVCFPAL TEGYVGALHE NRHGSAVQIR RRKASGDPYW 60 AYSGAYGPEH WVTSSVSCGG RHQSPIDILD QYARVGEEYQ ELQLDGFDNE SSNKTWMKNT 120 GKTVAILLKD DYFVSGAGLP GRFKAEKVEF HWGHSNGSAG SEHSINGRRF PVEMQIFFYN 180 PDDFDSFQTA ISENRIIGAM AIFFQVSPRD NSALDPIIHG LKGVVHHEKE TFLDPFVLRD 240 LLPASLGSYY RYTGSLTTPP CSEIVEWIVF RRPVPISYHQ LEAFYSIFTT EQQDHVKSVE 300 YLRNNFRPQQ RLHDRVVSKS AVRDSWNHDM TDFLENPLGT EASKVCSSPP IHMKVQPLNQ 360 TALQVSWSQP ETIYHPPIMN YMISYSWTKN EDEKEKTFTK DSDKDLKATI SHVSPDSLYL 420 FRVQAVCRND MRSDFSQTML FQANTTRIFQ GTRIVKTGVP TASPASSADM APISSGSSTW 480 TSSGIPFSFV SMATGMGPSS SGSQATVASV VTSTLLAGLG FGGGGISSFP STVWPTRLPT 540 AASASKQAAR PVLATTEALA SPGPDGDSSP TKDGEGTEEG EKDEKSESED GEREHEEDGE 600 KDSEKKEKSG VTHAAEERNQ TEPSPTPSSP NRTAEGGHQT IPGHEQDHTA VPTDQTGGRR 660 DAGPGLDPDM VTSTQVPPTA TEEQYAGSDP KRPEMPSKKP MSRGDRFSED SRFITVNPAE 720 KNTSGMISRP APGRMEWIIP LIVVSALTFV CLILLIAVLV YWRGCNKIKS KGFPRRFREV 780 PSSGERGEKG SRKCFQTAHF YVEDSSSPRV VPNESIPIIP IPDDMEAIPV KQFVKHIGEL 840 YSNNQHGFSE DFEEVQRCTA DMNITAEHSN HPENKHKNRY INILAYDHSR VKLRPLPGKD 900 SKHSDYINAN YVDGYNKAKA YIATQGPLKS TFEDFWRMIW EQNTGIIVMI TNLVEKGRRK 960 CDQYWPTENS EEYGNIIVTL KSTKIHACYT VRRFSIRNTK VKKGQKGNPK GRQNERVVIQ 1020 YHYTQWPDMG VPEYALPVLT FVRRSSAARM PETGPVLVHC SAGVGRTGTY IVIDSMLQQI 1080 KDKSTVNVLG FLKHIRTQRN YLVQTEEQYI FIHDALLEAI LGKETEVSSN QLHSYVNSIL 1140 IPGVGGKTRL EKQFKLVTQC NAKYVECFSA QKECNKEKNR NSSVVPSERA RVGLAPLPGM 1200 KGTDYINASY IMGYYRSNEF IITQHPLPHT TKDFWRMIWD HNAQIIVMLP DNQSLAEDEF 1260 VYWPSREESM NCEAFTVTLI SKDRLCLSNE EQIIIHDFIL EATQDDYVLE VRHFQCPKWP 1320 NPDAPISSTF ELINVIKEEA LTRDGPTIVH DEYGAVSAGM LCALTTLSQQ LENENAVDVF 1380 QVAKMINLMR PGVFTDIEQY QFIYKAMLSL VSTKENGNGP MTVDKNGAVL IADESDPAES 1440 MESLV 1446 |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 1) | MESH:D013274 ; Stomach Neoplasms |
| GWASdb (count: 88) (view all) | rs9808938; Multiple complex diseases; Null
rs938959; Multiple complex diseases; Null rs4447759; Multiple complex diseases; Null rs4580548; Multiple complex diseases; Null rs4580548; Alcohol dependence; alcohol dependence rs13326767; Multiple complex diseases; Null |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 16) (view all) | 1021 NERVVIQYHYTQWPD dbPAF
1023 RVVIQYHYTQWPDMG dbPAF 1034 PDMGVPEYALPVLTF dbPAF 1164 VTQCNAKYVECFSAQ dbPAF 1182 NKEKNRNSSVVPSER dbPAF 1307 LEATQDDYVLEVRHF dbPAF |
| Ubiquitination (count: 5) | 1083 MLQQIKDKSTVNVLG PLMD
831 DMEAIPVKQFVKHIG PLMD 835 IPVKQFVKHIGELYS PLMD 902 PLPGKDSKHSDYINA PLMD 929 IATQGPLKSTFEDFW PLMD |
| Glycation (count: 2) | 222 DPIIHGLKGVVHHEK PLMD
229 KGVVHHEKETFLDPF PLMD |
| Malonylation (count: 1) | 1172 VECFSAQKECNKEKN PLMD |
| Network | Interaction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| A | B | Source | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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