P14635

PTMD Annotation Information

※ Protein Information

Tag Content
UniProt Accession CCNB1_HUMAN; P14635;
Entrez ID 891
GenBank Protein ID
GenBank Nucleotide ID
Protein Name G2/mitotic-specific cyclin-B1
Gene Name CCNB1; CCNB
Organism Homo sapiens
NCBI Taxa ID 9606
Functional DescriptionEssential for the control of the cell cycle at the G2/M (mitosis) transition.
Sequence
(Fasta)		MALRVTRNSK INAENKAKIN MAGAKRVPTA PAATSKPGLR PRTALGDIGN KVSEQLQAKM 60
PMKKEAKPSA TGKVIDKKLP KPLEKVPMLV PVPVSEPVPE PEPEPEPEPV KEEKLSPEPI 120
LVDTASPSPM ETSGCAPAEE DLCQAFSDVI LAVNDVDAED GADPNLCSEY VKDIYAYLRQ 180
LEEEQAVRPK YLLGREVTGN MRAILIDWLV QVQMKFRLLQ ETMYMTVSII DRFMQNNCVP 240
KKMLQLVGVT AMFIASKYEE MYPPEIGDFA FVTDNTYTKH QIRQMEMKIL RALNFGLGRP 300
LPLHFLRRAS KIGEVDVEQH TLAKYLMELT MLDYDMVHFP PSQIAAGAFC LALKILDNGE 360
WTPTLQHYLS YTEESLLPVM QHLAKNVVMV NQGLTKHMTV KNKYATSKHA KISTLPQLNS 420
ALVQDLAKAV AKV 434

※ PTM-Disease Association

NumPTMDiseaseCell TypeTypePTM SitePMID
1Serine PhosphorylationVulvar cancerUS12625849598
[Reference]: Expression of CDK1(Tyr15), pCDK1(Thr161), Cyclin B1 (total) and pCyclin B1(Ser126) in vulvar squamous cell carcinoma and their relations with clinicopatological features and prognosis.

※ Disease Cross-ref Annotation

DatabaseAnnotation
CTD (Curated)
(count: 1)		MESH:D011085 ; Polycystic Ovary Syndrome

※ PTM Sites

PTM Modification Sites
Phosphorylation
(count: 17)
(view all)		 116       PVKEEKLSPEPILVD     dbPAF
126       PILVDTASPSPMETS     dbPAF
128       LVDTASPSPMETSGC     dbPAF
133       SPSPMETSGCAPAEE     dbPAF
147       EDLCQAFSDVILAVN     dbPAF
177       YVKDIYAYLRQLEEE     dbPAF
Acetylation
(count: 6)		 10        LRVTRNSKINAENKA     PLMD
25        KINMAGAKRVPTAPA     PLMD
311       HFLRRASKIGEVDVE     PLMD
51        ALGDIGNKVSEQLQA     PLMD
59        VSEQLQAKMPMKKEA     PLMD
73        AKPSATGKVIDKKLP     PLMD
Ubiquitination
(count: 12)
(view all)		 111       EPEPEPVKEEKLSPE     PLMD
190       EEQAVRPKYLLGREV     PLMD
25        KINMAGAKRVPTAPA     PLMD
279       VTDNTYTKHQIRQME     PLMD
311       HFLRRASKIGEVDVE     PLMD
36        TAPAATSKPGLRPRT     PLMD

※ Protein-Protein Interaction

NetworkInteraction
ABSource