| Tag | Content |
|---|---|
| UniProt Accession | MYBB_HUMAN; P10244; |
| Entrez ID | 4605 |
| GenBank Protein ID | NM_001278610.1; NM_002466.3; |
| GenBank Nucleotide ID | NP_001265539.1; NP_002457.1; |
| Protein Name | Myb-related protein B (B-Myb) (Myb-like protein 2) |
| Gene Name | MYBL2; BMYB |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. |
| Sequence (Fasta) | MSRRTRCEDL DELHYQDTDS DVPEQRDSKC KVKWTHEEDE QLRALVRQFG QQDWKFLASH 60 FPNRTDQQCQ YRWLRVLNPD LVKGPWTKEE DQKVIELVKK YGTKQWTLIA KHLKGRLGKQ 120 CRERWHNHLN PEVKKSCWTE EEDRIICEAH KVLGNRWAEI AKMLPGRTDN AVKNHWNSTI 180 KRKVDTGGFL SESKDCKPPV YLLLELEDKD GLQSAQPTEG QGSLLTNWPS VPPTIKEEEN 240 SEEELAAATT SKEQEPIGTD LDAVRTPEPL EEFPKREDQE GSPPETSLPY KWVVEAANLL 300 IPAVGSSLSE ALDLIESDPD AWCDLSKFDL PEEPSAEDSI NNSLVQLQAS HQQQVLPPRQ 360 PSALVPSVTE YRLDGHTISD LSRSSRGELI PISPSTEVGG SGIGTPPSVL KRQRKRRVAL 420 SPVTENSTSL SFLDSCNSLT PKSTPVKTLP FSPSQFLNFW NKQDTLELES PSLTSTPVCS 480 QKVVVTTPLH RDKTPLHQKH AAFVTPDQKY SMDNTPHTPT PFKNALEKYG PLKPLPQTPH 540 LEEDLKEVLR SEAGIELIIE DDIRPEKQKR KPGLRRSPIK KVRKSLALDI VDEDVKLMMS 600 TLPKSLSLPT TAPSNSSSLT LSGIKEDNSL LNQGFLQAKP EKAAVAQKPR SHFTTPAPMS 660 SAWKTVACGG TRDQLFMQEK ARQLLGRLKP SHTSRTLILS 701 |
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| Database | Annotation |
|---|---|
| GWASdb (count: 1) | rs285171; Alcohol and nictotine co-dependence; alcohol dependence|nicotine dependence |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 47) (view all) | 136 LNPEVKKSCWTEEED dbPAF
15 EDLDELHYQDTDSDV dbPAF 168 AKMLPGRTDNAVKNH dbPAF 178 AVKNHWNSTIKRKVD dbPAF 18 DELHYQDTDSDVPEQ dbPAF 20 LHYQDTDSDVPEQRD dbPAF |
| Acetylation (count: 3) | 533 LEKYGPLKPLPQTPH PLMD
639 NQGFLQAKPEKAAVA PLMD 648 EKAAVAQKPRSHFTT PLMD |
| Ubiquitination (count: 5) | 135 HLNPEVKKSCWTEEE PLMD
411 GTPPSVLKRQRKRRV PLMD 533 LEKYGPLKPLPQTPH PLMD 584 SPIKKVRKSLALDIV PLMD 664 APMSSAWKTVACGGT PLMD |
| Sumoylation (count: 12) (view all) | 104 LVKKYGTKQWTLIAK PLMD
194 GGFLSESKDCKPPVY PLMD 197 LSESKDCKPPVYLLL PLMD 275 EPLEEFPKREDQEGS PLMD 447 TPKSTPVKTLPFSPS PLMD 509 AFVTPDQKYSMDNTP PLMD |
| Network | Interaction | ||
|---|---|---|---|
| A | B | Source | |