Tag | Content |
---|---|
UniProt Accession | IBP1_HUMAN; P08833; |
Entrez ID | 3484 |
GenBank Protein ID | |
GenBank Nucleotide ID | |
Protein Name | Insulin-like growth factor-binding protein 1 (IBP-1) (IGF-binding protein 1) (IGFBP-1) (Placental protein 12) (PP12) |
Gene Name | IGFBP1; IBP1 |
Organism | Homo sapiens |
NCBI Taxa ID | 9606 |
Functional Description | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. |
Sequence (Fasta) | MSEVPVARVW LVLLLLTVQV GVTAGAPWQC APCSAEKLAL CPPVSASCSE VTRSAGCGCC 60 PMCALPLGAA CGVATARCAR GLSCRALPGE QQPLHALTRG QGACVQESDA SAPHAAEAGS 120 PESPESTEIT EEELLDNFHL MAPSEEDHSI LWDAISTYDG SKALHVTNIK KWKEPCRIEL 180 YRVVESLAKA QETSGEEISK FYLPNCNKNG FYHSRQCETS MDGEAGLCWC VYPWNGKRIP 240 GSPEIRGDPN CQIYFNVQN |
|
Database | Annotation |
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CTD (Curated) (count: 9) (view all) | MESH:D000022
; Abortion, Spontaneous MESH:D058186 ; Acute Kidney Injury MESH:D003110 ; Colonic Neoplasms MESH:D064420 ; Drug-Related Side Effects and Adverse Reactions MESH:D004715 ; Endometriosis MESH:D008103 ; Liver Cirrhosis |
DisGeNet (Curated) (count: 9) (view all) | C0000786; Spontaneous abortion
C0009375; Colonic Neoplasms C0014175; Endometriosis C0023890; Liver Cirrhosis C0023892; Biliary cirrhosis C0023893; Liver Cirrhosis, Experimental |
GWASdb (count: 2) | rs1874479; Obesity (extreme); obesity
rs4619; Height; Null |
PTM | Modification Sites |
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Phosphorylation (count: 9) (view all) | 108 QGACVQESDASAPHA dbPAF
120 PHAAEAGSPESPEST dbPAF 123 AEAGSPESPESTEIT dbPAF 126 GSPESPESTEITEEE dbPAF 127 SPESPESTEITEEEL dbPAF 144 NFHLMAPSEEDHSIL dbPAF |