| Tag | Content |
|---|---|
| UniProt Accession | ALBU_HUMAN; P02768; |
| Entrez ID | 213 |
| GenBank Protein ID | |
| GenBank Nucleotide ID | |
| Protein Name | Serum albumin |
| Gene Name | ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341 |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. |
| Sequence (Fasta) | MKWVTFISLL FLFSSAYSRG VFRRDAHKSE VAHRFKDLGE ENFKALVLIA FAQYLQQCPF 60 EDHVKLVNEV TEFAKTCVAD ESAENCDKSL HTLFGDKLCT VATLRETYGE MADCCAKQEP 120 ERNECFLQHK DDNPNLPRLV RPEVDVMCTA FHDNEETFLK KYLYEIARRH PYFYAPELLF 180 FAKRYKAAFT ECCQAADKAA CLLPKLDELR DEGKASSAKQ RLKCASLQKF GERAFKAWAV 240 ARLSQRFPKA EFAEVSKLVT DLTKVHTECC HGDLLECADD RADLAKYICE NQDSISSKLK 300 ECCEKPLLEK SHCIAEVEND EMPADLPSLA ADFVESKDVC KNYAEAKDVF LGMFLYEYAR 360 RHPDYSVVLL LRLAKTYETT LEKCCAAADP HECYAKVFDE FKPLVEEPQN LIKQNCELFE 420 QLGEYKFQNA LLVRYTKKVP QVSTPTLVEV SRNLGKVGSK CCKHPEAKRM PCAEDYLSVV 480 LNQLCVLHEK TPVSDRVTKC CTESLVNRRP CFSALEVDET YVPKEFNAET FTFHADICTL 540 SEKERQIKKQ TALVELVKHK PKATKEQLKA VMDDFAAFVE KCCKADDKET CFAEEGKKLV 600 AASQAALGL |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 63) (view all) | MESH:D058186
; Acute Kidney Injury MESH:C538231 ; Adenocarcinoma of lung MESH:D000799 ; Angioedema MESH:D001002 ; Anuria MESH:D001169 ; Arthritis, Experimental MESH:D053713 ; Azoospermia |
| DisGeNet (Curated) (count: 67) (view all) | C0002994; Angioedema
C0003460; Anuria C0004509; Azoospermia C0006111; Brain Diseases C0007222; Cardiovascular Diseases C0007786; Brain Ischemia |
| HGMD (count: 76) (view all) | CD084019; Analbuminaemia; Small deletions
CD941565; Albumin variant; Small deletions CD910474; Analbuminaemia; Small deletions CD023226; Analbuminaemia; Small deletions CG890193; Albumin variant; Gross deletions CI941821; Analbuminaemia; Small insertions |
| GWASdb (count: 3) | rs3775486; C-Reactive Protein; metabolic syndrome X|type 2 diabetes mellitus|hypertension|myocardial infarction
rs16849331; Type 2 diabetes; type 2 diabetes mellitus rs16849331; Suicide attempts in bipolar disorder; bipolar disorder |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 42) (view all) | 107 TVATLRETYGEMADC dbPAF
108 VATLRETYGEMADCC dbPAF 14 ISLLFLFSSAYSRGV dbPAF 162 EETFLKKYLYEIARR dbPAF 164 TFLKKYLYEIARRHP dbPAF 17 LFLFSSAYSRGVFRR dbPAF |
| Acetylation (count: 59) (view all) | 117 EMADCCAKQEPERNE PLMD
130 NECFLQHKDDNPNLP PLMD 160 DNEETFLKKYLYEIA PLMD 161 NEETFLKKYLYEIAR PLMD 183 PELLFFAKRYKAAFT PLMD 186 LFFAKRYKAAFTECC PLMD |
| Ubiquitination (count: 2) | 229 LKCASLQKFGERAFK PLMD
499 PVSDRVTKCCTESLV PLMD |
| Glycation (count: 58) (view all) | 117 EMADCCAKQEPERNE PLMD
130 NECFLQHKDDNPNLP PLMD 160 DNEETFLKKYLYEIA PLMD 161 NEETFLKKYLYEIAR PLMD 183 PELLFFAKRYKAAFT PLMD 186 LFFAKRYKAAFTECC PLMD |
| Methylation (count: 2) | 558 TALVELVKHKPKATK PLMD
75 NEVTEFAKTCVADES PLMD |