| Tag | Content |
|---|---|
| UniProt Accession | SODC_HUMAN; P00441; |
| Entrez ID | 6647 |
| GenBank Protein ID | |
| GenBank Nucleotide ID | |
| Protein Name | Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1) |
| Gene Name | SOD1 |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | Destroys radicals which are normally produced within the cells and which are toxic to biological systems. |
| Sequence (Fasta) | MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE FGDNTAGCTS 60 AGPHFNPLSR KHGGPKDEER HVGDLGNVTA DKDGVADVSI EDSVISLSGD HCIIGRTLVV 120 HEKADDLGKG GNEESTKTGN AGSRLACGVI GIAQ 155 |
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| Database | Annotation |
|---|---|
| CTD (Curated) (count: 63) (view all) | MESH:D000690
; Amyotrophic Lateral Sclerosis MESH:C531617 ; Amyotrophic lateral sclerosis 1 MESH:D018798 ; Anemia, Iron-Deficiency MESH:D001018 ; Aortic Diseases MESH:D001238 ; Asphyxia Neonatorum MESH:D001249 ; Asthma |
| HGMD (count: 129) (view all) | CD941793; Amyotrophic lateral sclerosis; Small deletions
CD034939; Amyotrophic lateral sclerosis; Small deletions CD091834; Amyotrophic lateral sclerosis; Small deletions CD962162; Amyotrophic lateral sclerosis; Small deletions CD034940; Amyotrophic lateral sclerosis; Small deletions CD045905; Amyotrophic lateral sclerosis; Small deletions |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 11) (view all) | 103 ADVSIEDSVISLSGD dbPAF
106 SIEDSVISLSGDHCI dbPAF 108 EDSVISLSGDHCIIG dbPAF 26 INFEQKESNGPVKVW dbPAF 3 *****MATKAVCVLK dbPAF 35 GPVKVWGSIKGLTEG dbPAF |
| Acetylation (count: 6) | 10 TKAVCVLKGDGPVQG PLMD
123 RTLVVHEKADDLGKG PLMD 129 EKADDLGKGGNEEST PLMD 137 GGNEESTKTGNAGSR PLMD 24 GIINFEQKESNGPVK PLMD 4 ****MATKAVCVLKG PLMD |
| Ubiquitination (count: 11) (view all) | 10 TKAVCVLKGDGPVQG PLMD
123 RTLVVHEKADDLGKG PLMD 129 EKADDLGKGGNEEST PLMD 137 GGNEESTKTGNAGSR PLMD 24 GIINFEQKESNGPVK PLMD 31 KESNGPVKVWGSIKG PLMD |
| Sumoylation (count: 1) | 76 SRKHGGPKDEERHVG PLMD |
| Glycation (count: 6) | 10 TKAVCVLKGDGPVQG PLMD
123 RTLVVHEKADDLGKG PLMD 129 EKADDLGKGGNEEST PLMD 31 KESNGPVKVWGSIKG PLMD 37 VKVWGSIKGLTEGLH PLMD 4 ****MATKAVCVLKG PLMD |
| Malonylation (count: 1) | 123 RTLVVHEKADDLGKG PLMD |
| Succinylation (count: 3) | 10 TKAVCVLKGDGPVQG PLMD
123 RTLVVHEKADDLGKG PLMD 76 SRKHGGPKDEERHVG PLMD |
| Network | Interaction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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