| Tag | Content |
|---|---|
| UniProt Accession | TPPP_HUMAN; O94811; |
| Entrez ID | 11076 |
| GenBank Protein ID | NM_007030.2; XM_005248237.3; XM_017008994.1; |
| GenBank Nucleotide ID | NP_008961.1; XP_005248294.2; XP_016864483.1; |
| Protein Name | Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha) |
| Gene Name | TPPP; TPPP1 |
| Organism | Homo sapiens |
| NCBI Taxa ID | 9606 |
| Functional Description | May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. |
| Sequence (Fasta) | MADKAKPAKA ANRTPPKSPG DPSKDRAAKR LSLESEGAGE GAAASPELSA LEEAFRRFAV 60 HGDARATGRE MHGKNWSKLC KDCQVIDGRN VTVTDVDIVF SKIKGKSCRT ITFEQFQEAL 120 EELAKKRFKD KSSEEAVREV HRLIEGKAPI ISGVTKAISS PTVSRLTDTT KFTGSHKERF 180 DPSGKGKGKA GRVDLVDESG YVSGYKHAGT YDQKVQGGK |
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| Database | Annotation |
|---|---|
| DisGeNet (Curated) (count: 1) | C3826462; Depression in children |
| GWASdb (count: 1) | rs386057; Otitis media (chronic/recurrent); otitis media |
| PTM | Modification Sites |
|---|---|
| Phosphorylation (count: 15) (view all) | 107 FSKIKGKSCRTITFE dbPAF
14 PAKAANRTPPKSPGD dbPAF 152 EGKAPIISGVTKAIS dbPAF 155 APIISGVTKAISSPT dbPAF 159 SGVTKAISSPTVSRL dbPAF 160 GVTKAISSPTVSRLT dbPAF |
| Methylation (count: 1) | 78 MHGKNWSKLCKDCQV PLMD |
| Network | Interaction | ||
|---|---|---|---|
| A | B | Source | |